Description
The hSMUG1 enzyme from New England Biolabs is designed to excise deoxyuracil and its derivatives from DNA, leaving an oxidized intermediate. This enzyme exhibits 50% activity on single-stranded DNA (ssDNA) compared to double-stranded DNA (dsDNA). It is a valuable tool for oxidative DNA damage studies and single-cell gel electrophoresis, commonly known as the Comet assay. Manufactured to stringent quality control standards, this enzyme ensures reliable performance in critical research applications.
- Excises deoxyuracil and derivatives.
- 50% activity on ssDNA vs dsDNA.
- Suitable for oxidative DNA damage studies.
- Used in Comet assays.
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