Corning Fiberglass Prefilter 63 mm Square for use with 500 ml Funnel 100 Filters

Description

Corning 431412 Glass Fiber Prefilters – 63 mm Square, Non-Sterile

The Corning 431412 is a square glass fiber prefilter designed specifically for integration with Corning 500 mL bottle-top vacuum filtration systems and filter funnels. Manufactured from binder-free borosilicate glass fiber, this 63 mm square membrane is engineered to be placed directly on top of the primary sterilizing filter. By acting as an initial depth filter, it actively traps large particulate matter, cellular debris, and dense lipid complexes. This critical pre-filtration step prevents the premature clogging of the underlying microporous membrane, maintaining rapid flow rates and maximizing the total fluid throughput of turbid biological solutions.

Technical Performance and Design

• Borosilicate Glass Fiber: The binder-free depth-filter matrix provides exceptional dirt-handling capacity and resists structural breakdown even under sustained vacuum pressure.

• Optimized Geometry: The 63 mm x 63 mm square profile is precision-cut to provide edge-to-edge coverage over the primary membrane of 500 mL Corning vacuum funnels, eliminating fluid bypass.

• Chemically Inert: The pure glass fiber construction offers broad chemical compatibility and completely prevents the leaching of unwanted binders or extractables into the filtered sample.

• Enhanced Throughput: By shielding the delicate 0.22 µm or 0.45 µm final filter from heavy particulate loads, the prefilter dramatically increases the total volume of fluid that can be processed before the system stalls.

Product Specifications

• Catalog Number: 431412

• Material: Borosilicate Glass Fiber (BGF)

• Dimensions: 63 mm x 63 mm (Square)

• System Compatibility: 500 mL Corning Filter Funnels

• Sterility: Non-Sterile

• Packaging: Bulk Case of 100 Filters

Key Benefits & Applications

• Cell Culture Media Preparation: The standard choice for clarifying serum-heavy or heavily supplemented liquid media that would otherwise rapidly foul standard polyethersulfone (PES) or cellulose acetate membranes.

• Viscous Fluid Handling: Essential for processing dense protein solutions, crude cellular lysates, and complex fermentation broths during downstream biochemical purification.

• Environmental & Analytical Filtration: Effective for pre-filtering turbid environmental water samples, soil extracts, or sludge prior to fine quantitative analysis.

• Cost-Effective Workflow: Eliminates the need to use multiple expensive sterile filter units for a single turbid sample by significantly extending the functional lifespan of one vacuum funnel.

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