Description
Description
Guanidine Hydrochloride ≥98% 1 Kg
Synonym: Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
- CAS Number 50-01-1
- Linear Formula NH2C(=NH)NH2 · HCl
- Molecular Weight 95.53
- Beilstein/REAXYS Number 3591990
- EC Number 200-002-3
- MDL number MFCD00013026
- PubChem Substance ID 57651288
- NACRES NA.55
| assay | ≥98% |
| pH | (25 °C, 4.6 – 6/573 g/L) |
| mp | 180-185 °C (lit.) |
| solubility | H2O: 6 M, clear (100 Hazen) |
| SMILES string | Cl[H].NC(N)=N |
| InChI | 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H |
| InChI key | PJJJBBJSCAKJQF-UHFFFAOYSA-N |
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.





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