Description
Description
Guanidine Thiocyanate For Molecular Biology ≥99% 250 Gram
Synonym: Guanidinium rhodanide, Guanidinium thiocyanate
- CAS Number 593-84-0
- Linear Formula NH2C(=NH)NH2 · HSCN
- Molecular Weight 118.16
- Beilstein/REAXYS Number 3563461
- EC Number 209-812-1
- MDL number MFCD00013027
- PubChem Substance ID 24895367
- NACRES NA.31
| grade | for molecular biology |
| assay | ≥99% |
| mp | 120-122 °C (lit.) |
| cation traces | Ba: ≤5 ppm |
| Fe: ≤5 ppm | |
| K: ≤0.005% | |
| Na: ≤0.5% | |
| heavy metals (as Pb): ≤5 ppm | |
| Featured Industry | Agriculture |
| foreign activity | DNase, RNase, none detected |
| SMILES string | SC#N.NC(N)=N |
| InChI | 1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H |
| InChI key | ZJYYHGLJYGJLLN-UHFFFAOYSA-N |
Application
Guanidine thiocyanate has been used:
• for the lysis of colorectal adenocarcinoma cell line prior to RNA isolation
• as a PCR inhibitor in triplex mitochondrial DNA (mtDNA) qPCR assay
• for DNA extraction from cerebrospinal fluid (CSF)
Chaotropic agent and strong denaturant; solubilizes cells.
GHS05, GHS07
Signal word Danger
Hazard statements H302 + H312 + H332-H314-H412
Precautionary statements P260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Supplemental Hazard Statements Contact with acids liberates very toxic gas.
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RIDADR UN 1759 8 / PGIII
WGK Germany 2
Documents
Safety Data Sheet
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