Description
Description
MES hydrate ≥99.5% Titration Ph 2.5-4.0 0.5 M In H2O Bioxtra 50 Gram
Synonym: 2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid
- CAS Number 1266615-59-1
- Empirical Formula (Hill Notation) C6H13NO4S · xH2O
- Molecular Weight 195.24 (anhydrous basis)
- MDL number MFCD00149409
- eCl@ss 32129211
- PubChem Substance ID 329818007
- NACRES NA.25
| Quality Level | 300 |
| 400 | |
| product line | BioXtra |
| assay | ≥99.5% (titration) |
| impurities | Insoluble matter, passes filter test |
| ign. residue (900°C) | ≤0.05% |
| pH | 2.5-4.0 (0.5 M in H2O) |
| useful pH range | 5.5 – 6.7 |
| pKa | 6.1 |
| solubility | H2O: 0.5 M, clear, colorless |
| anion traces | chloride (Cl-): ≤0.005% |
| cation traces | Al: ≤0.0005% |
| As: ≤0.0001% | |
| Ba: ≤0.0005% | |
| Bi: ≤0.0005% | |
| Ca: ≤0.002% | |
| Cd: ≤0.0005% | |
| Co: ≤0.0005% | |
| Cr: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Li: ≤0.0005% | |
| Mg: ≤0.0005% | |
| Mn: ≤0.0005% | |
| Mo: ≤0.0005% | |
| Na: ≤0.005% | |
| Ni: ≤0.0005% | |
| Pb: ≤0.0005% | |
| Sr: ≤0.0005% | |
| Zn: ≤0.0005% | |
| absorption | ≤0.020 at 280 in H2O at 0.5 M |
| ≤0.025 at 260 in H2O at 0.5 M | |
| SMILES string | O.OS(=O)(=O)CCN1CCOCC1 |
| InChI | 1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2 |
| InChI key | MIIIXQJBDGSIKL-UHFFFAOYSA-N |
General description
MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.
Application
MES Hydrate has been used:
• As a component of extraction buffer in the extraction of the enzyme BACE1
• As a component of the reaction mixture for the measurement of 5,10-methenyltetrahydrofolate synthetase (MTHFS) enzyme activity in fibroblasts
• As a component of MES coupling buffer during the coupling of mAb or GST-fusion proteins to carboxylate-modified polystyrene latex (CML) beads
Documents
Safety Data Sheet
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