Repligen Reservoir with 4-Port Cap 2L PETG Flat Bottom Reservoir

Description

Repligen ACBT-2-D Reservoir – 2 L, PET, Flat Bottom, 4-Port Cap

The Repligen ACBT-2-D is a high-capacity, 2-Liter single-use process reservoir engineered specifically for Tangential Flow Filtration (TFF) and diafiltration workflows. Designed for seamless integration with automated benchtop TFF systems such as the KrosFlo KR2i, this vessel is constructed from durable, high-clarity Polyethylene Terephthalate (PET). Unlike standard lab bottles, it features a specialized 4-port cap equipped with internal dip tubes. This architecture allows process engineers to simultaneously manage the feed draw, retentate return, continuous buffer addition, and system venting within a completely closed environment. The flat bottom design provides excellent stability on crowded benchtops and magnetic stir plates, making it a reliable workhorse for processing proteins, monoclonal antibodies, and viral vectors.

Technical Performance and Design

• 4-Port Cap Configuration: The specialized multi-port cap allows for complex, simultaneous fluid transfers without breaking the closed sterile envelope, eliminating the risk of external contamination during prolonged TFF runs.

• Integrated Dip Tubes: The internal dip tubes extend toward the bottom of the vessel to ensure that retentate is returned below the liquid surface. This submerged return completely eliminates splashing, dramatically reducing foam generation and shear-induced protein denaturation.

• High-Clarity PET Construction: Molded from shatter-resistant PET, offering the optical clarity of glass for easy visual monitoring of the retentate volume, sample turbidity, and mixing efficiency.

• Flat Bottom Stability: The wide, flat base ensures the 2-Liter vessel remains stable when placed on magnetic stir plates, promoting the even mixing of diafiltration buffers and sample feeds without tipping under the weight of heavy tubing lines.

Product Specifications

• Catalog Number: ACBT-2-D

• Capacity: 2000 mL (2 Liters)

• Vessel Profile: Flat Bottom

• Bottle Material: Polyethylene Terephthalate (PET)

• Cap Configuration: 4-Port Cap with Dip Tubes

• System Compatibility: Benchtop TFF Systems (e.g., KrosFlo KR2i, KMPi)

Key Benefits & Applications

• Continuous Diafiltration: The multi-port setup allows for automated, constant-volume buffer exchange, drastically speeding up sample preparation, desalting, and formulation steps.

• Protein & Viral Vector Processing: The ideal feed reservoir for the concentration and washing of delicate biological structures that are highly susceptible to shear stress and air-entrapment.

• Plug-and-Play Efficiency: As a ready-to-use assembly, it completely bypasses the need for cleaning validation and intricate tubing assembly, getting your TFF process up and running immediately.

• Robust Tubing Management: The dedicated ports prevent the messy and hazardous “spaghetti” of tubing that occurs when trying to jam multiple lines into a standard two-port or open-top container.

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