Description
Thermo Scientific Nalgene 4116-2800 Erlenmeyer Flask – 2800 mL, Baffled Bottom, PETG
The Thermo Scientific Nalgene 4116-2800 is a high-capacity 2.8L Fernbach-style Erlenmeyer flask designed for large-scale suspension cell culture and aerobic fermentation. Constructed from high-clarity, medical-grade PETG, this flask provides the optical transparency of glass with the safety and impact resistance of high-performance plastic. The flask is engineered with a baffled bottom, which promotes vigorous agitation and increases the surface-to-volume ratio during shaking to optimize gas exchange. Supplied sterile and non-pyrogenic, the 4116-2800 is a reliable, single-use alternative to glass flasks, eliminating the need for time-consuming cleaning and validation while reducing the risk of cross-contamination in biopharmaceutical production.
Technical Performance and Design
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Triple-Baffled Bottom: The molded-in baffles disrupt the laminar flow of the media during orbital shaking, creating a turbulent environment that significantly enhances oxygenation for high-demand aerobic cultures.
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High-Clarity PETG: Manufactured from USP Class VI polyethylene terephthalate glycol, offering excellent visibility for monitoring cell growth and media color changes without the breakage risk of borosilicate glass.
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Vented Screw Closure: Includes a 70 mm vented cap with a 0.2 µm hydrophobic membrane, allowing for continuous, sterile gas exchange while maintaining a secure barrier against airborne contaminants.
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Sterile & Disposable: Gamma irradiated to a Sterility Assurance Level (SAL) of 10⁻⁶, these flasks are designed for single-use “plug and play” workflows, saving on labor and energy costs associated with autoclaving.
Product Specifications
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Catalog Number: 4116-2800
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Capacity: 2800 mL (2.8 Liters)
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Material: PETG (USP Class VI)
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Bottom Shape: Baffled
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Closure Size: 70 mm
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Sterility: Sterile (Gamma Irradiated)
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Certifications: Non-pyrogenic, Non-cytotoxic, and Animal Derived Component-Free (ADCF).
Key Benefits & Applications
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Large-Scale Protein Expression: Ideal for the cultivation of E. coli, yeast, and other microbial strains used in the production of recombinant proteins and enzymes.
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Seed Train Expansion: Provides the high oxygen transfer rates necessary to quickly scale up cell densities before inoculation into large-scale bioreactors.
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Laboratory Safety: The shatterproof PETG construction protects personnel and high-value research by preventing the catastrophic spills and injuries common with large glass flasks.
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Standardized Footprint: Despite the large volume, the base is designed to fit standard large-capacity orbital shaker clamps, ensuring easy integration into existing laboratory equipment.
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