Description
Thermo Scientific 66430 Slide-A-Lyzer™ Cassette Buoy (White)
The Thermo Scientific 66430 is a specialized flotation accessory designed for use with the original format of Slide-A-Lyzer™ Dialysis Cassettes. Engineered to provide optimal buoyancy, this buoy ensures that the dialysis cassette remains suspended in a vertical orientation within the buffer beaker. This vertical positioning is critical for maximizing the exposed membrane surface area, which facilitates the fastest possible dialysis kinetics. Manufactured from high-density, chemically resistant foam, the 66430 is a reusable lab staple that provides a secure, friction-fit grip on the cassette frame, preventing it from sinking or resting against the container walls where diffusion could be hindered.
Technical Performance and Design
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Optimized Vertical Suspension: Holds the cassette in the ideal orientation to ensure that both sides of the dialysis membrane are fully in contact with the buffer, maintaining a high concentration gradient for efficient salt and contaminant removal.
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Universal Original-Fit: Specifically designed to accommodate the frames of 0.5 ml, 3.0 ml, and 12.0 ml original-style Slide-A-Lyzer™ cassettes.
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High-Density Construction: The closed-cell foam material is non-absorbent and resistant to common laboratory buffers, ensuring long-term durability and consistent buoyancy through repeated use.
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Friction-Fit Security: The precision-cut center slot provides a snug fit that keeps the cassette securely locked in place, even during moderate buffer stirring.
Product Specifications
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Catalog Number: 66430
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Compatible Cassettes: Slide-A-Lyzer™ Original Format (0.5 ml, 3 ml, 12 ml)
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Color: White
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Material: High-Density Synthetic Foam
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Capacity: Holds 1 Cassette per Buoy
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Packaging: Available as individual units or in packs of 10.
Key Benefits & Applications
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Enhanced Dialysis Efficiency: Prevents the cassette from resting at the bottom of the beaker, ensuring that magnetic stir bars can circulate buffer freely around the entire membrane.
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Sample Protection: Keeps the cassette away from the vortex and the stir bar at the bottom of the beaker, reducing the risk of physical damage to the delicate dialysis membrane.
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Benchtop Organization: Allows for easy retrieval of samples from large buffer volumes; the bright white color makes the sample location easy to identify even in large carboys or beakers.
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Reusable Design: Simply rinse with deionized water and air dry between uses, making it a cost-effective solution for routine protein purification and desalting workflows.
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